Understanding the immune system, immunity, and related diseases through data

23.12.2021 - Publications news

Domingues TD, Mourino H, Sepúlveda N. Analysis of cutoff point estimation for determining seropositivity in the context of SARS-CoV-2 infections. medRxiv 2021.12.20.21268100 (2021).

Stanculescu D, Sepúlveda N, Lim CL, Bergquist J. Lessons From Heat Stroke for Understanding Myalgic Encephalomyelitis/Chronic Fatigue Syndrome. Frontiers in Neurology 12:2258 (2021).

22.12.2021 - Immune-Stats Xmas challenge

This year there was a terrifying Xmas challenge for all of us: to create a short video about our achievements in 2021. The videos were presented in the last group meeting of the year. The votes for the best video were unanimous: João Malato! He created a funny and well-designed video about his ups and downs during the year. A must-see for all the PhD students who must deal with these yo-yo moments in motivation and productivity.

22.11.2021 - Visit and seminar at CHICAS, United Kingdom

Nuno Sepúlveda had the pleasure to visit the Centre of Health Informatics, Computing and Statistics (CHICAS) at Lancaster University, United Kingdom. He also delivered a talk about the three-sigma rule in serological data analysis of COVID-19 data. Twenty minutes of discussion with the audience! Thanks for the invitation, Emanuele Giorgi!

26.10.2021 - PhD title awarded to Tiago Domingues

The PhD journey has finished for Tiago Dias Domingues. He valiantly defended his thesis entitled "Finite mixture models based on Scale Mixtures of Skew-Normal distributions applied to Serological Data" from the Faculty of Sciences of University of Lisbon, Portugal. Congratulations, Tiago! A new stage of your academic life has just begun!

22.10.2021 - PhD examination

Nuno Sepúlveda was the external examiner of the PhD thesis entitled "Threshold-free statistical methods for the analysis of continuous health outcomes, with application to malaria serology" of the student Irene Kyomuhangi from Lancaster University, United Kingdom. She passed with minor corrections! Congratulation to Irene for a nice discussion and achievement!

27.09.2021 - Publications news

Fonseca A, Ramalhete SV, Mestre A, Pires das Neves R, Marreiros A, Castelo-Branco P, Roberto VP. Identification of colorectal cancer associated biomarkers: an integrated analysis of miRNA expression. Aging 13 (2021).

Dewasurendra R, Sepúlveda N, Chandrasekharan N, Karunaweera N, Gunawardena, S. Polymorphisms in rs915941 and rs915942: Are they associated with increased risk of G6PD enzyme deficiency in the Sri Lankan population?. Journal of the National Science Foundation of Sri Lanka, 49:157–168 (2021).

See other publications of the group.

18.08.2021 - ACE2 paper featured on Health Rising

Health rising has featured our latest Heliyon paper on SARS-CoV-2 receptor ACE2 in people with ME/CFS. Health Rising is a blog founded by Cort Johnson with the aim of understanding Chronic Fatigue Syndrome and Fibromyalgia. The blog is almost supported by donations and so please donate there!

04.08.2021 - Publications news

Malato J, Sotzny F, Bauer S, Freitag H, Fonseca A, Grabowska AD, Graça L, Cordeiro C, Nacul L, Lacerda EM, Castro-Marrero J, Scheibenbogen C, Westermeier F, Sepúlveda N. The SARS-CoV-2 receptor angiotensin-converting enzyme 2 (ACE2) in myalgic encephalomyelitis/chronic fatigue syndrome: A meta-analysis of public DNA methylation and gene expression data. Heliyon 7:e07665 (2021).

Sepúlveda N. Impact of genetic variation on the molecular mimicry between Anoctamin-2 and Epstein-Barr virus nuclear antigen 1 in Multiple Sclerosis. Immunol Lett 238:29-31 (2021).

See other publications of the group.

30.07.2021 - An allelic exclusion story!

Our guest speaker Jorge Carneiro will tell us his latest story about allelic exclusion in antigen receptors. Welcome to the Immune-Stats group, Jorge! I hope you feel proud of being part of the family!

More information on this link.

01.07.2021 - @MiNI, WAW, Poland

The team leader Nuno Sepúlveda began a two-year post at the Department of Mathematics and Information Science (MiNI) at Warsaw University of Technology, Poland. He will run the project entitled "Integrative analysis to discover candidate molecular mimicries between human and viral proteins with application to Myalgic Encephalomyelitis/Chronic Fatigue Syndrome and post-outbreak sequelae".

Click here for more information.

25.06.2021 - Where are your modes, Jose?

We had the pleasure of listening to Jose Ameijeiras-Alonso in our weekly group meeting. Thanks for sharing your knowledge about detecting multimodality in data, Jose!

Know more on this link.

Presentation at IMM meeting

Check João Malato talking about his PhD research about the impact of misclassification (or subgrouping) on association studies of ME/CFS.

Congratulations for a job well done, João!